Puerperal sepsis

Best Pract Res Clin Obstet Gynaecol. 2013 Dec;27(6):893-902. doi: 10.1016/j.bpobgyn.2013.07.004. Epub 2013 Aug 30.

Abstract

Infections during pregnancy are relatively prevalent, and the majority of cases are managed well in the community. Occasionally, however, infections may be life-threatening. Sepsis may be associated with multiple organ dysfunction and a high mortality. The treatment of sepsis is time critical and requires early fluid resuscitation and antibiotics. Early involvement of other specialties and allied health-care professionals to provide a multidisciplinary approach to patient care is important. Continuous monitoring of maternal vital signs and provision of supportive care for multiple organ dysfunction are best done within the intensive care unit. Despite advances in patient care, the mortality rate associated with maternal sepsis remains high. Health-care services in low-income countries face particular problems that account for an increased incidence of puerperal sepsis and maternal mortality. These include lack of access to health care, septic abortions and a greater incidence of human immunodeficiency virus. The key to management of sepsis is early recognition, aggressive resuscitation, antibiotic administration and source control.

Keywords: intensive care; resuscitation; sepsis.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / diagnosis*
  • Bacteremia / therapy*
  • Critical Care*
  • Developed Countries / statistics & numerical data
  • Developing Countries / statistics & numerical data
  • Early Diagnosis
  • Female
  • Fluid Therapy
  • Global Health / statistics & numerical data
  • Humans
  • Practice Guidelines as Topic
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / therapy
  • Puerperal Infection / diagnosis*
  • Puerperal Infection / epidemiology
  • Puerperal Infection / therapy*
  • Shock, Septic / diagnosis
  • Shock, Septic / therapy
  • Treatment Outcome
  • United Kingdom / epidemiology

Substances

  • Anti-Bacterial Agents