The main purpose of this study was to compare the effect of the 2 minimally invasive surgical techniques for treating axillary hyperhidrosis: superficial tumescent suction curettage and curettage only. A total of 22 patients diagnosed with axillary hyperhidrosis received one type of treatment at each side, randomized. Examinations were performed pre-operatively and at 3, 6 and 12 months following treatment. Sweating was measured by gravimetry and a new skin conductance method. Subjective rating of sweating was assessed by a visual analogue scale. Skin conductance was recorded during a stress-test including acoustic, mental and physical stressors. Five patients withdrew or did not meet for any follow-up examination, giving 17 subjects in total for data analysis. Significant reduction in sweating after surgery lasting at least 12 months was found based on skin conductance, gravimetry and visual analogue scale scoring. Comparison between types of treatment revealed a significantly better effect of tumescent suction curettage than curettage only.