A case of 5-FU-related severe toxicity associated with the p.Y186C DPYD variant

Clin Pharmacol Ther. 2014 Feb;95(2):136. doi: 10.1038/clpt.2013.183. Epub 2013 Sep 13.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use*
  • Black or African American / genetics*
  • Dihydrouracil Dehydrogenase (NADP) / genetics*
  • Female
  • Fluorouracil / therapeutic use*
  • Humans
  • Male
  • Neoplasms / drug therapy*

Substances

  • Antimetabolites, Antineoplastic
  • Dihydrouracil Dehydrogenase (NADP)
  • Fluorouracil