Orthotopic heart transplantation in two infants with histiocytoid cardiomyopathy and left ventricular non-compaction

Pediatr Transplant. 2013 Nov;17(7):E165-7. doi: 10.1111/petr.12141.

Abstract

HC is a rare cause of congestive heart failure that typically presents with malignant ventricular arrhythmias in infants, often requiring urgent intervention. Successful heart transplantation in a patient with HC has only been reported once (J Heart Lung Transplant 2004: 23: 902). The combination of HC with concurrent LVNC has only been described three times (Int J Legal Med 2009: 123: 47; Hum Pathol 2005: 36: 403; Pediatr Dev Pathol 2012: 15: 397). We report two rare cases of HC with LVNC in two infants presenting with cardiogenic shock, one requiring ECMO support who was successfully bridged to orthotopic heart transplantation with a Berlin Heart LVAD.

Keywords: cardiomyopathy; histiocytoid; pediatric transplantation.

Publication types

  • Case Reports

MeSH terms

  • Cardiomyopathies / congenital*
  • Cardiomyopathies / therapy
  • Cardiomyopathy, Dilated / therapy
  • Electron Transport Complex III / deficiency*
  • Extracorporeal Membrane Oxygenation
  • Female
  • Heart / physiopathology
  • Heart Failure / therapy
  • Heart Transplantation / methods*
  • Heart Ventricles / physiopathology*
  • Heart-Assist Devices
  • Humans
  • Infant
  • Male
  • Shock, Cardiogenic / therapy
  • Treatment Outcome

Substances

  • Electron Transport Complex III

Supplementary concepts

  • Cardiomyopathy, infantile histiocytoid