Daytime leg pain after overnight continuous positive airway pressure titration

Yun Li; Zhe Li; Fei Lei; Junying Zhou; Xiangdong Tang

doi:10.1016/j.jns.2013.10.036

Daytime leg pain after overnight continuous positive airway pressure titration

J Neurol Sci. 2014 Jan 15;336(1-2):281-3. doi: 10.1016/j.jns.2013.10.036. Epub 2013 Oct 29.

Authors

Yun Li¹, Zhe Li¹, Fei Lei¹, Junying Zhou¹, Xiangdong Tang²

Affiliations

¹ Sleep Medicine Center, Translational Neuroscience Center, Department of Otolaryngology, West China Hospital, Sichuan University, Chengdu, China.
² Sleep Medicine Center, Translational Neuroscience Center, Department of Otolaryngology, West China Hospital, Sichuan University, Chengdu, China. Electronic address: xiangdong.tang@gmail.com.

PMID: 24210774
DOI: 10.1016/j.jns.2013.10.036

Abstract

We report a case that showed transitional, severe emergent periodic limb movements during sleep (PLMS) in the first continuous positive airway pressure (CPAP) titration night and mild PLMS in the 3rd and 20th nights of CPAP titration in a 56-year-old woman after she was found to have severe obstructive sleep apnea (OSA). Severe PLMS in the initial CPAP night unexpectedly resulted in acute leg muscle soreness in the second morning. The case suggests that CPAP therapy in patients who suffer from severe OSA may provide a unique opportunity to look into the pathological mechanism of PLMS.

Keywords: CPAP-emergent PLMS; Continuous positive airway pressure titration; Daytime sleepiness; Leg pain; Obstructive sleep apnea; Periodic limb movements during sleep.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Continuous Positive Airway Pressure / adverse effects*
Female
Humans
Leg / pathology*
Middle Aged
Nocturnal Myoclonus Syndrome / diagnosis*
Nocturnal Myoclonus Syndrome / etiology
Pain / diagnosis*
Pain / etiology
Polysomnography / methods
Sleep / physiology