A small cog in a big wheel: PIK3CA mutations in colorectal cancer

J Natl Cancer Inst. 2013 Dec 4;105(23):1775-6. doi: 10.1093/jnci/djt330. Epub 2013 Nov 14.

Authors

Sebastian Stintzing¹, Heinz-Josef Lenz

Affiliation

¹ Affiliation of authors: USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (SS, H-JL).

PMID: 24231451
DOI: 10.1093/jnci/djt330

No abstract available

Publication types

Editorial

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biomarkers, Tumor / genetics*
Camptothecin / administration & dosage
Camptothecin / analogs & derivatives
Chemotherapy, Adjuvant
Class I Phosphatidylinositol 3-Kinases
Clinical Trials as Topic
Colorectal Neoplasms / drug therapy
Colorectal Neoplasms / genetics*
Colorectal Neoplasms / pathology
Colorectal Neoplasms / surgery
Fluorouracil / administration & dosage
Humans
Irinotecan
Leucovorin / administration & dosage
Molecular Targeted Therapy* / methods
Mutation*
Neoplasm Staging
Phosphatidylinositol 3-Kinases / genetics*

Substances

Biomarkers, Tumor
Irinotecan
Phosphatidylinositol 3-Kinases
Class I Phosphatidylinositol 3-Kinases
PIK3CA protein, human
Leucovorin
Fluorouracil
Camptothecin