Glufosinate herbicide intoxication causing unconsciousness, convulsion, and 6th cranial nerve palsy

J Korean Med Sci. 2013 Nov;28(11):1687-9. doi: 10.3346/jkms.2013.28.11.1687. Epub 2013 Oct 31.

Abstract

Although glufosinate ammonium herbicides are considered safe when used properly, ingestion of the undiluted form can cause grave outcomes. Recently, we treated a 34-yr-old man who ingested glufosinate ammonium herbicide. In the course of treatment, the patient developed apnea, mental deterioration, and sixth cranial nerve palsy; he has since been discharged with full recovery after intensive care. This case report describes the clinical features of glufosinate intoxication with a focus on sixth cranial nerve palsy. Our observation suggests that neurologic manifestations after ingestion of a "low-grade toxicity herbicide" are variable and more complex than that was previously considered.

Keywords: Abducens Nerve Disease; Glufosinate Ammonium; Neurologic Manifestations.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abducens Nerve Diseases / chemically induced*
  • Abducens Nerve Diseases / drug therapy
  • Adult
  • Aminobutyrates / poisoning*
  • Enzyme Inhibitors / poisoning
  • Herbicides / poisoning*
  • Humans
  • Male
  • Seizures / chemically induced
  • Surface-Active Agents / poisoning
  • Unconsciousness / chemically induced

Substances

  • Aminobutyrates
  • Enzyme Inhibitors
  • Herbicides
  • Surface-Active Agents
  • phosphinothricin