IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta

M H Abumaree; P Brownbill; G Burton; C Castillo; L Chamley; B A Croy; S Drewlo; C Dunk; S Girard; S Hansson; S Jones; A Jurisicova; R Lewis; M Letarte; M Parast; C Pehrson; D Rappolee; H Schneider; D Tannetta; S Varmuza; C Wadsack; A E Wallace; C Zenerino; G E Lash

doi:10.1016/j.placenta.2013.11.009

IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta

Placenta. 2014 Feb:35 Suppl:S15-9. doi: 10.1016/j.placenta.2013.11.009. Epub 2013 Nov 28.

Authors

M H Abumaree¹, P Brownbill², G Burton³, C Castillo⁴, L Chamley⁵, B A Croy⁶, S Drewlo⁷, C Dunk⁸, S Girard², S Hansson⁹, S Jones², A Jurisicova¹⁰, R Lewis¹¹, M Letarte¹², M Parast¹³, C Pehrson¹⁴, D Rappolee⁷, H Schneider¹⁵, D Tannetta¹⁶, S Varmuza¹⁷, C Wadsack¹⁸, A E Wallace¹⁹, C Zenerino²⁰, G E Lash²¹

Affiliations

¹ College of Medicine, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Centre, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.
² Maternal and Fetal Health Research Centre, Institute of Human Development, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK; St. Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
³ Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.
⁴ Institute for Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
⁵ Department of Obstetrics and Gynaecology, The University of Auckland, Auckland, New Zealand.
⁶ Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
⁷ Department of Obstetrics and Gynaecology, Wayne State University School of Medicine, CS Mott Centre for Human Growth and Development, Detroit, MI, USA.
⁸ Research Centre for Women's and Infants Health, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
⁹ Division of Obstetrics and Gynaecology, Department of Clinical Sciences, University of Lund, Lund, Sweden.
¹⁰ Lunenfeld-Tannebaum Research Institute and Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada.
¹¹ Faculty of Medicine, University of Southampton, Institute for Developmental Sciences, Southampton General Hospital, Southampton, UK.
¹² Hospital for Sick Children and Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
¹³ Department of Pathology, University of San Diego, San Diego, CA, USA.
¹⁴ Centre of Medical Parasitology, Department of International Health, Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Department of Infectious diseases, Copenhagen University Hospital, Copenhagen, Denmark.
¹⁵ Department of Obstetrics and Gynaecology, Insel Spital, University of Bern, Bern, Switzerland.
¹⁶ Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK.
¹⁷ Department of Systems Biology, University of Toronto, Toronto, Ontario, Canada.
¹⁸ Department of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria.
¹⁹ St George's Hospital, University of London, London, UK.
²⁰ Department of Surgical Sciences, University of Turin, Turin, Italy.
²¹ Reproductive and Vascular Biology Group, Institute of Cellular Medicine, Newcastle University, 3rd Floor, William Leech Building, Newcastle upon Tyne NE2 4HH, UK. Electronic address: gendie.lash@ncl.ac.uk.

PMID: 24321780
DOI: 10.1016/j.placenta.2013.11.009

Abstract

Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2013 there were twelve themed workshops, three of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of placental function, cell turnover and immunology: 1) immunology; 2) novel determinants of placental cell fate; 3) dual perfusion of human placental tissue.

Keywords: Amino acid transport; Fetoplacental vascular tone; Immunology; Lipid transport; Malaria parasite; Placental cell fate; Placental dual perfusion; Syncytiotrophoblast microvesicles.

Publication types

Congress

MeSH terms

Animals
Female
Humans
Perfusion / methods
Placenta / immunology*
Placentation*
Pregnancy / immunology*

Grants and funding

MR/J003360/1/MRC_/Medical Research Council/United Kingdom