Central venous catheter-related infections in hematology and oncology: 2012 updated guidelines on diagnosis, management and prevention by the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology

Ann Oncol. 2014 May;25(5):936-47. doi: 10.1093/annonc/mdt545. Epub 2014 Jan 7.

Abstract

Background: Cancer patients are at increased risk for central venous catheter-related infections (CRIs). Thus, a comprehensive, practical and evidence-based guideline on CRI in patients with malignancies is warranted.

Patients and methods: A panel of experts by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) has developed a guideline on CRI in cancer patients. Literature searches of the PubMed, Medline and Cochrane databases were carried out and consensus discussions were held.

Results: Recommendations on diagnosis, management and prevention of CRI in cancer patients are made, and the strength of the recommendation and the level of evidence are presented.

Conclusion: This guideline is an evidence-based approach to the diagnosis, management and prevention of CRI in cancer patients.

Keywords: catheter infection; central venous catheter; guidelines; neutropenia.

Publication types

  • Practice Guideline

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy
  • Candidiasis / prevention & control
  • Catheter-Related Infections / diagnosis*
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / prevention & control
  • Catheterization / methods
  • Central Venous Catheters / microbiology
  • Disease Management
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / prevention & control
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / prevention & control
  • Hematology
  • Humans
  • Medical Oncology

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents