A historical case of amelogenesis imperfecta: Giovanna of Austria, Grand Duchess of Tuscany (1547-1578)

Eur J Oral Sci. 2014 Feb;122(1):1-6. doi: 10.1111/eos.12097. Epub 2013 Oct 31.

Abstract

The skeletal remains of Giovanna of Austria (1547-1578), daughter of the Emperor Ferdinand I of Habsburg (1503-1564) and first wife of the Grand Duke of Tuscany, Francesco I (1541-1587), exhumed from the Basilica of San Lorenzo in Florence, were submitted to paleopathological study. Examination of the dentition, which was in a good state of preservation, showed maxillary retrognathism, together with a caries lesion, moderate periodontal disease, malposition of the upper second premolars and tooth wear. Furthermore, several horizontal grooves were observed in both the buccal and the lingual crown surfaces of almost all teeth, especially the anterior ones. The orthopantomogram showed hypomineralized enamel and alveolar bone loss. Two third-molar teeth were investigated using micro-computed tomography (micro-CT) analysis, revealing highly irregular enamel caps with reduced average thickness. The observed features suggest a diagnosis of hypoplastic amelogenesis imperfecta, a developmental condition affecting enamel formation.

Keywords: Florence; Habsburg; Medici; Renaissance; enamel defects.

Publication types

  • Biography
  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amelogenesis Imperfecta / history*
  • Austria
  • Famous Persons*
  • Female
  • History, 16th Century
  • Humans
  • Italy

Personal name as subject

  • Giovanna of Austria Medici