Neoplastic meningitis presenting with dysphagia and bilateral vocal cord paralysis

Laryngoscope. 2014 Aug;124(8):1912-4. doi: 10.1002/lary.24640. Epub 2014 Mar 19.

Abstract

Neoplastic meningitis is the infiltration of the leptomeninges and subarachnoid space by tumor cells occurring in 3% to 5% of patients with systemic malignancies. Most cases present with multifocal neurological symptoms that vary according to the central nervous system territory involved. Here, we describe the first reported case to our knowledge of neoplastic meningitis causing bilateral vocal cord paralysis. Early diagnosis of this progressive disease process is essential to achieving a better treatment response and improved survival. This report demonstrates that neoplastic meningitis should be considered in the investigation of bilateral vocal cord paralysis, particularly in patients with a history of metastatic disease.

Keywords: Vocal cord paralysis; cranial nerve neoplasms; meningeal neoplasms.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Deglutition Disorders / etiology*
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / complications*
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Male
  • Meningitis / complications*
  • Meningitis / etiology
  • Neoplasm Invasiveness
  • Spinal Cord Neoplasms / complications*
  • Spinal Cord Neoplasms / pathology
  • Vocal Cord Paralysis / etiology*