Carbapenem-resistant Enterobacteriaceae rectal screening during an outbreak of New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae at an acute care hospital

Infect Control Hosp Epidemiol. 2014 Apr;35(4):434-6. doi: 10.1086/675597.

Abstract

We describe the results of carbapenem-resistant Enterobacteriaceae (CRE) screening as part of an outbreak investigation of New Delhi metallo-β-lactamase-producing CRE at a tertiary care university teaching hospital. The manual method for CRE screening was useful for detecting patients with asymptomatic CRE carriage but was time-consuming and costly.

MeSH terms

  • Adult
  • Aged
  • Carbapenems / pharmacology*
  • Colorado
  • Confidence Intervals
  • Disease Outbreaks*
  • Female
  • Hospitals, Teaching
  • Humans
  • Intensive Care Units
  • Klebsiella Infections / diagnosis*
  • Klebsiella pneumoniae / enzymology
  • Klebsiella pneumoniae / isolation & purification*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Population Surveillance
  • Rectum / microbiology*
  • Young Adult
  • beta-Lactamases / biosynthesis*

Substances

  • Carbapenems
  • beta-Lactamases
  • beta-lactamase NDM-1