Changes observed in multiparametric prostate magnetic resonance imaging characteristics correlate with histopathological development of chronic granulomatous prostatitis after intravesical Bacillus Calmette-Guerin therapy

J Comput Assist Tomogr. 2014 Mar-Apr;38(2):274-6. doi: 10.1097/RCT.0b013e3182aac58a.

Abstract

Administration of Bacillus Calmette-Guerin (BCG) has been shown to cause granulomatous prostatitis, a rare inflammatory process that can be mistaken for prostate cancer. We present a case of a 78-year-old man on active surveillance for prostate cancer with a subsequent diagnosis of high-grade urothelial carcinoma. After intravesical BCG therapy, he developed chronic granulomatous prostatitis. We present serial magnetic resonance imaging and biopsy data demonstrating the time interval between BCG administration and the manifestation of chronic granulomatous prostatitis.

Publication types

  • Case Reports
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • BCG Vaccine / adverse effects*
  • Carcinoma, Transitional Cell / diagnosis*
  • Carcinoma, Transitional Cell / surgery
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / diagnosis
  • Prostatitis / chemically induced*
  • Prostatitis / diagnosis*
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / surgery

Substances

  • BCG Vaccine
  • Prostate-Specific Antigen