Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy

Muscle Nerve. 2014 Jul;50(1):47-51. doi: 10.1002/mus.24109. Epub 2014 May 2.

Abstract

Introduction: We determined health plan paid costs and healthcare resource usage of patients with chronic inflammatory demyelinating polyneuropathy (CIDP).

Methods: CIDP patients from 9 U.S. commercial health plans with claims in 2011 were identified from the Accordant Health Services claims database. We examined demographics, prevalence of comorbidities, prescribed drugs, place of service, and mean annual health plan paid costs per patient.

Results: From 6.5 million covered lives, 73 (56% men; mean age 47) met study entry criteria. The most prescribed therapies were intravenous immunoglobulin (IVIg) (26% of patients), gabapentin (26%), and prednisone (16%). The annual health plan paid cost was $56,953. Pharmacy cost was the major cost driver (57% of the total), and IVIg totaled 90% of the pharmacy costs.

Conclusions: Healthcare costs for CIDP patients are substantial, with a large burden in pharmacy usage. Studies are needed to determine optimal long-term treatment strategies for CIDP, particularly related to IVIg.

Keywords: CIDP; chronic inflammatory polyradiculoneuropathy; cost analysis; costs; health care cost; intravenous immune globulin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Algorithms
  • Amines / economics
  • Amines / therapeutic use
  • Analgesics / economics
  • Analgesics / therapeutic use
  • Anti-Inflammatory Agents / economics
  • Anti-Inflammatory Agents / therapeutic use
  • Comorbidity
  • Costs and Cost Analysis
  • Cyclohexanecarboxylic Acids / economics
  • Cyclohexanecarboxylic Acids / therapeutic use
  • Drug Costs
  • Electromyography
  • Female
  • Gabapentin
  • Humans
  • Immunoglobulins, Intravenous / economics
  • Immunoglobulins, Intravenous / therapeutic use
  • Insurance, Health / economics*
  • International Classification of Diseases
  • Male
  • Middle Aged
  • Neural Conduction
  • Neurologic Examination
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / drug therapy
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / economics*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / epidemiology*
  • Prednisolone / economics
  • Prednisolone / therapeutic use
  • Socioeconomic Factors
  • United States / epidemiology
  • Young Adult
  • gamma-Aminobutyric Acid / economics
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Amines
  • Analgesics
  • Anti-Inflammatory Agents
  • Cyclohexanecarboxylic Acids
  • Immunoglobulins, Intravenous
  • gamma-Aminobutyric Acid
  • Gabapentin
  • Prednisolone