Detection of Neisseria meningitidis from negative blood cultures and cerebrospinal fluid with the FilmArray blood culture identification panel

Joe Pardo; Kenneth P Klinker; Samuel J Borgert; Brittany M Butler; Kenneth H Rand; Nicole M Iovine

doi:10.1128/JCM.00352-14

Detection of Neisseria meningitidis from negative blood cultures and cerebrospinal fluid with the FilmArray blood culture identification panel

J Clin Microbiol. 2014 Jun;52(6):2262-4. doi: 10.1128/JCM.00352-14. Epub 2014 Apr 16.

Authors

Joe Pardo¹, Kenneth P Klinker¹, Samuel J Borgert¹, Brittany M Butler², Kenneth H Rand², Nicole M Iovine³

Affiliations

¹ Department of Pharmacy, UF Health Shands Hospital, Gainesville, Florida, USA.
² Department of Pathology, University of Florida, Gainesville, Florida, USA.
³ Department of Pathology, University of Florida, Gainesville, Florida, USA iovinnm@medicine.ufl.edu.

Abstract

The FilmArray blood culture identification (BCID) panel is a rapid molecular diagnostic test approved for use with positive blood culture material. We describe a fatal case of meningococcemia with central nervous system (CNS) involvement detected using the BCID test with culture-negative blood and cerebrospinal fluid.

Publication types

Case Reports

MeSH terms

Bacteremia / complications
Bacteremia / diagnosis*
Bacteremia / microbiology
Bacteriological Techniques*
Blood / microbiology*
Cerebrospinal Fluid / microbiology*
Fatal Outcome
Female
Humans
Infant
Meningitis, Meningococcal / complications
Meningitis, Meningococcal / diagnosis*
Meningitis, Meningococcal / microbiology
Molecular Diagnostic Techniques*
Neisseria meningitidis / isolation & purification*