Open innovation is the new buzz, with initiatives popping up left and right. Here, we give a personal perspective on a very successful, knowledge-driven innovation initiated in an academia- industry alliance, which culminated in technology platforms that enable the generation of therapeutic antibodies with novel properties. To start, we provide a general background on open innovation in the drug development field.
Keywords: Duobody technology; Fab-arm exchange; Open innovation; Technology platform; bispecific antibodies; drug development; immunotherapy.