Self-regulatory fatigue, quality of life, health behaviors, and coping in patients with hematologic malignancies

Ann Behav Med. 2014 Dec;48(3):411-23. doi: 10.1007/s12160-014-9621-z.

Abstract

Background: Self-regulatory fatigue may play an important role in a complex medical illness.

Purpose: Examine associations between self-regulatory fatigue, quality of life, and health behaviors in patients pre- (N = 213) and 1-year post-hematopoietic stem cell transplantation (HSCT; N = 140). Associations between self-regulatory fatigue and coping strategies pre-HSCT were also examined.

Method: Pre- and 1-year post-HSCT data collection. Hierarchical linear regression modeling.

Results: Higher self-regulatory fatigue pre-HSCT associated with lower overall, physical, social, emotional, and functional quality of life pre- (p's < .001) and 1-year post-HSCT (p's < .01); lower physical activity pre-HSCT (p < .02) and post-HSCT (p < .03) and less healthy nutritional intake post-HSCT (p < .01); changes (i.e., decrease) in quality of life and healthy nutrition over the follow-up year; and use of avoidance coping strategies pre-HSCT (p's < .001).

Conclusion: This is the first study to show self-regulatory fatigue pre-HSCT relating to decreased quality of life and health behaviors, and predicting changes in these variables 1-year post-HSCT.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adaptation, Psychological / physiology*
  • Adult
  • Aged
  • Fatigue / psychology*
  • Female
  • Follow-Up Studies
  • Health Behavior*
  • Hematologic Neoplasms / psychology*
  • Hematologic Neoplasms / therapy
  • Hematopoietic Stem Cell Transplantation / psychology*
  • Humans
  • Male
  • Middle Aged
  • Quality of Life / psychology*
  • Treatment Outcome
  • Young Adult