Successful increase in uterine volume and subsequent pregnancy in a patient with a history of radiation and chemotherapy

Miriam S Krause; M Symmes Johnson; Abigail A Delaney; Henry Bohler Jr; Steven T Nakajima

doi:10.1016/j.ajog.2014.05.018

Successful increase in uterine volume and subsequent pregnancy in a patient with a history of radiation and chemotherapy

Am J Obstet Gynecol. 2014 Aug;211(2):e1-2. doi: 10.1016/j.ajog.2014.05.018. Epub 2014 May 15.

Authors

Miriam S Krause¹, M Symmes Johnson², Abigail A Delaney², Henry Bohler Jr², Steven T Nakajima²

Affiliations

¹ Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY. Electronic address: ms.krause@yahoo.de.
² Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, KY.

PMID: 24837034
DOI: 10.1016/j.ajog.2014.05.018

Abstract

A 26-year-old woman with a history of cranial radiation and chemotherapy desired pregnancy. Pelvic ultrasound scanning demonstrated a small uterine volume of 7 mL. After 25 weeks of estrogen therapy, her uterine volume increased to 37 mL. The patient had an uncomplicated pregnancy with the use of donor oocytes and delivered a term healthy daughter.

Keywords: estradiol treatment; pregnancy; radiation; uterine volume.

Publication types

Case Reports

MeSH terms

Administration, Intravaginal
Administration, Oral
Adult
Antineoplastic Agents / adverse effects
Blastocyst
Cerebellar Neoplasms / drug therapy
Cerebellar Neoplasms / radiotherapy
Embryo Transfer
Estradiol / administration & dosage*
Estrogens / administration & dosage*
Female
Humans
Infant, Newborn
Infertility, Female / etiology
Infertility, Female / therapy
Live Birth*
Medulloblastoma / drug therapy
Medulloblastoma / radiotherapy
Oocyte Donation
Pregnancy
Primary Ovarian Insufficiency / complications
Primary Ovarian Insufficiency / etiology
Ultrasonography
Uterus / diagnostic imaging
Uterus / drug effects*
Uterus / growth & development*

Substances

Antineoplastic Agents
Estrogens
Estradiol