Percutaneous sclerotherapy of foot venous malformations: evaluation of clinical response

Clin Radiol. 2014 Sep;69(9):931-8. doi: 10.1016/j.crad.2014.04.014. Epub 2014 May 24.

Abstract

Aim: To evaluate a single institutional experience with percutaneous sclerotherapy of venous malformations (VM) of the foot.

Materials and methods: Sixteen patients (mean age 14.6 years; range 6-27.3 years), who underwent 34 sclerotherapy procedures were retrospectively analysed. Technical success, Puig classification, VM size reduction, and the complication rate were evaluated. In procedures in which C-arm computed tomography (CT) was performed, the VM-to-skin surface distance was measured. Additionally, an e-mail-based questionnaire to evaluate the response to sclerotherapy was answered by the patients.

Results: Technical success was 97%. The mean number of procedures per patient was 2.1 (range 1-5). In all procedures, sodium tetradecyl sulphate foam was used. Appropriate follow-up was available for 29/33 procedures (88%). Post-procedural complications occurred after 6/29 procedures (21%), all of which were self-limited skin complications. C-arm CT was performed in 19/33 procedures (58%). The lesion-to-skin surface distance was significantly shorter in patients with skin post-procedural complications (p < 0.001). The e-mail-based questionnaire was completed by 13/16 patients (81%). Decrease in swelling, improvement of foot function and a significant decrease in pain (p = 0.003) was reported. No patient reported dis-improvement after sclerotherapy.

Conclusion: Percutaneous sclerotherapy is an effective option for treating foot VMs. Skin complication rates are higher with shorter VM-to-skin surface distance.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Foot Diseases / diagnostic imaging
  • Foot Diseases / therapy*
  • Humans
  • Male
  • Radiography, Interventional*
  • Retrospective Studies
  • Sclerosing Solutions / therapeutic use*
  • Sclerotherapy*
  • Surveys and Questionnaires
  • Tomography, X-Ray Computed*
  • Treatment Outcome
  • Vascular Malformations / diagnostic imaging
  • Vascular Malformations / therapy*

Substances

  • Sclerosing Solutions