Protein electrochemistry using graphene-based nano-assembly: an ultrasensitive electrochemical detection of protein molecules via nanoparticle-electrode collisions

Chem Commun (Camb). 2014 Aug 4;50(60):8197-200. doi: 10.1039/c4cc03384a.

Abstract

We describe a new electrochemical detection approach towards single protein molecules (microperoxidase-11, MP-11), which are attached to the surface of graphene nanosheets. The non-covalently functionalized graphene nanosheets exhibit enhanced electroactive surface area, where amplified redox current is produced when graphene nanosheets collide with the electrode.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques*
  • Electrochemistry*
  • Electrodes*
  • Graphite / chemistry*
  • Nanoparticles / chemistry*
  • Nanotechnology / methods*
  • Oxidation-Reduction
  • Peroxidases / chemistry*

Substances

  • Graphite
  • Peroxidases
  • microperoxidase