Purpose: At St. Erik Eye Hospital in Stockholm, Sweden, ocular tumors of apical height above 6 mm are treated with brachytherapy, using iodine-125 seeds attached to a gold alloy plaque while the treatment planning is performed assuming homogeneous water surroundings. The aim of this work was to investigate the dose-modifying effects of the plaque and the seed fixating silicone rubber glue.
Methods and materials: The impact of the gold plaque and silicone rubber glue was studied with the Monte Carlo N-particle transport code, version 5.
Results: For the 2 cm most proximal to the plaque surface along the plaque's central axis, the eyeball received 104.6-93.0% of the dose in all-water conditions.
Conclusions: The 0.3 mm thick layer of silicone rubber glue, used for seed fixation, attenuates photons little enough to allow characteristic X-rays from the gold alloy plaque to reach the eyeball. Close to the plaque, the dose rates were higher with the plaque and glue present, than in homogeneous water conditions. This is in contrast to what has been reported for more commonly used eye plaques, demonstrating the importance of investigating the dosimetry of individual treatment systems.
Keywords: (125)I; Brachytherapy; Dosimetry; Eye plaque; Monte Carlo simulations; Ocular melanoma.
Copyright © 2014 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.