1 ICON Development Solution (D.E.), San Antonio, Texas; Departments of Pediatrics, Medicine, Cellular and Integrative Physiology, and Biochemistry and Molecular Biology (R.G.M.), Indiana University School of Medicine, Indianapolis, Indiana 46202; and Section of Pediatric Diabetes and Endocrinology (J.A.K.), Baylor College of Medicine and Diabetes and Endocrinology Service, Texas Children's Hospital, Houston, Texas 77030.