Perioperative analgesia outcomes and strategies

Amit Prabhakar; Kenneth F Mancuso; Christopher Paul Owen; Jonathan Lissauer; Christopher K Merritt; Richard D Urman; Alan David Kaye

doi:10.1016/j.bpa.2014.04.005

Perioperative analgesia outcomes and strategies

Best Pract Res Clin Anaesthesiol. 2014 Jun;28(2):105-15. doi: 10.1016/j.bpa.2014.04.005. Epub 2014 May 22.

Authors

Amit Prabhakar¹, Kenneth F Mancuso², Christopher Paul Owen³, Jonathan Lissauer⁴, Christopher K Merritt⁵, Richard D Urman⁶, Alan David Kaye⁷

Affiliations

¹ Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA. Electronic address: amitprabhakar7@gmail.com.
² Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA. Electronic address: kmancu@lsuhsc.edu.
³ Ochsner Clinic Foundation Anesthesiology Department, New Orleans, LA 70121, USA. Electronic address: chowen@ochsner.org.
⁴ Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA. Electronic address: jonlissauer@gmail.com.
⁵ Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA. Electronic address: ckmerritt@gmail.com.
⁶ Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: rurman@partners.org.
⁷ Department of Anesthesiology, Louisiana State University School of Medicine, New Orleans, LA, USA. Electronic address: alankaye44@hotmail.com.

PMID: 24993432
DOI: 10.1016/j.bpa.2014.04.005

Abstract

Despite an appreciation for many unwanted physiological effects from inadequate pain postoperative relief, moderate to severe postoperative pain remains commonplace. Though treatment options have evolved in recent years, including improvement in medications, multimodal regimens, and regional anesthetic techniques, including ultrasound and continuous catheters, outcomes data indicate that many of these strategies are associated with varying degrees of morbidity and mortality. This review focuses on the importance of effective postoperative analgesia and both short- and long-term effects associated with inadequate management. A careful literature review of emphasizing treatment options and potential pathogenesis associated with these strategies is emphasized in this review.

Keywords: acetaminophen; acute pain; multimodal analgesia; nonsteroidals; regional anesthesia.

Publication types

Review

MeSH terms

Analgesia / methods*
Anesthesia, Conduction
Humans
Pain Management / methods*
Perioperative Care / methods*
Treatment Outcome