Analysis of a panel of rapidly growing mycobacteria for resistance to aldehyde-based disinfectants

Am J Infect Control. 2014 Aug;42(8):932-4. doi: 10.1016/j.ajic.2014.05.014.

Abstract

After several accounts across the globe of mycobacteria outbreaks associated with medical procedures and aldehyde disinfectants resistance, we undertook an analysis of mycobacteria isolated from patients seen in a hospital in the United States between 1994 and 2008 to determine prevalence of resistance to aldehyde-based disinfectants. Out of the 117 clinical isolates screened, 6 isolates belonging to the emerging Mycobacterium abscessus group were found to display significant levels of resistance to glutaraldehyde and ortho-phthalaldehyde.

Keywords: Glutaraldehyde; Ortho-phthalaldehyde.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disinfectants / pharmacology*
  • Drug Resistance, Bacterial*
  • Glutaral / pharmacology*
  • Humans
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Nontuberculous Mycobacteria / drug effects*
  • Nontuberculous Mycobacteria / isolation & purification
  • United States
  • o-Phthalaldehyde / pharmacology*

Substances

  • Disinfectants
  • o-Phthalaldehyde
  • Glutaral