The burden of pneumococcal disease is high worldwide, mainly among elderly and immunosuppressed patients. Vaccines are important tools as preventive strategy for this population. There are two types of pneumococcal vaccines approved for adults, these are polysaccharide and conjugate, which are inactivated, have different serotype composition and immunogenicity. As new studies are available for pneumococcal conjugate vaccine, new recommendations have been made for its use in adults.