A pilot randomized trial of levator injections versus physical therapy for treatment of pelvic floor myalgia and sexual pain

Int Urogynecol J. 2015 Jun;26(6):845-52. doi: 10.1007/s00192-014-2606-4. Epub 2014 Dec 20.

Abstract

Introduction and hypothesis: Our aim was to determine the effects of pelvic floor physical therapy (PT) and levator-directed trigger-point injections (LTPI) on sexual function and levator-related pelvic pain.

Study design: A randomized trial among women with pelvic floor myalgia (PFM) was performed wherein participants received either PT or LTPI. Pain was assessed and 1 month posttreatment completion. Levator-based pain was assessed using a numeric rating scale (NRS) and the Patient Global Impression of Improvement (PGI-I) scale. Sexual function was assessed using the Female Sexual Function Index (FSFI).

Results: Twenty-nine women completed the study (17 had PT, 12 had LTPI). Both groups reported reduction in vaginal pain: mean NRS change from baseline of 4.47 [standard deviation (SD) 2.12) for PT and 4.67 (SD 1.72) for LTPI (p = 0.8)]. A >50 % improvement in NRS was documented among 59 % of women receiving PT and 58 % receiving LTPI (p = 1.0). Consistent with NRS scores, mean PGI-I score was 2.50 (SD 1.17) for PT and 2.17 (SD 1.01) for LTPI (p = 0.5). Mean change in FSFI favored PT [PT +8.87 (SD 5.60), LTPI +4.00 (SD 5.24), p = 0.04], reflecting improvement in the sexual pain domain favoring PT (p = 0.02). However, the time in weeks to effect improvement favored LTPI if controlling for the degree of change in NRS (p = 0.01) and FSFI (p = 0.01).

Conclusions: Vaginal myalgia and sex-related pain improved with pelvic floor PT and LTPI. Time-to-effect improvement and significance of therapy are dependent on treatment type.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anesthetics, Local / administration & dosage*
  • Anus Diseases / therapy*
  • Bupivacaine / administration & dosage*
  • Female
  • Glucocorticoids / administration & dosage*
  • Humans
  • Injections / methods*
  • Massage*
  • Middle Aged
  • Myalgia / therapy*
  • Myofascial Pain Syndromes / therapy*
  • Pain
  • Pelvic Floor Disorders
  • Pilot Projects
  • Treatment Outcome
  • Triamcinolone / administration & dosage*
  • Trigger Points

Substances

  • Anesthetics, Local
  • Glucocorticoids
  • Triamcinolone
  • Bupivacaine

Supplementary concepts

  • Levator syndrome