A biological plausible Generalized Leaky Integrate-and-Fire neuron model

Zhenzhong Wang; Lilin Guo; Malek Adjouadi

doi:10.1109/EMBC.2014.6945192

A biological plausible Generalized Leaky Integrate-and-Fire neuron model

Annu Int Conf IEEE Eng Med Biol Soc. 2014:2014:6810-3. doi: 10.1109/EMBC.2014.6945192.

Authors

Zhenzhong Wang, Lilin Guo, Malek Adjouadi

PMID: 25571560
DOI: 10.1109/EMBC.2014.6945192

Abstract

This study introduces a new Generalized Leaky Integrate-and-Fire (GLIF) neuron model. Unlike Normal Leaky Integrate-and-Fire (NLIF) models, the leaking resistor in the GLIF model equation is assumed to be variable, and an additional term would have the bias current added to the model equation in order to improve the accuracy. Adjusting the parameters defined for the leaking resistor and bias current, a GLIF model could be accurately matched to any Hodgkin-Huxley (HH) model and be able to reproduce plausible biological neuron behaviors.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Action Potentials / physiology*
Algorithms*
Computer Simulation
Models, Neurological*
Neurons / physiology*