Abstract
Spheroids present a model for tumor behavior in vivo. In NMR studies, a problem of spheroid adhesion occurs. Here, we present a method which overcomes this problem and show the variations in phosphate metabolite concentrations as well as the rate of glucose metabolism as a function of spheroid age.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adenosine Triphosphate / metabolism
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Breast Neoplasms / metabolism*
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Carcinoma, Intraductal, Noninfiltrating / metabolism*
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Female
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Humans
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Magnetic Resonance Spectroscopy / methods*
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Phosphates / metabolism
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Tumor Cells, Cultured
Substances
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Phosphates
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Adenosine Triphosphate