P2X7/PANX1 as a new target for melanoma?

Exp Dermatol. 2015 May;24(5):336-7. doi: 10.1111/exd.12633. Epub 2015 Mar 9.
No abstract available

Keywords: IL-1β; P2X7; inflammasome; melanoma; purinergic receptors.

MeSH terms

  • Animals
  • Connexins / agonists*
  • Humans
  • Inflammasomes / drug effects
  • Inflammasomes / physiology
  • Interleukin-1beta / biosynthesis
  • Melanoma / physiopathology*
  • Melanoma / therapy*
  • Mice
  • Nerve Tissue Proteins / agonists*
  • Purinergic P2X Receptor Agonists / pharmacology
  • Receptors, Purinergic P2X7 / physiology*

Substances

  • Connexins
  • Inflammasomes
  • Interleukin-1beta
  • Nerve Tissue Proteins
  • P2RX7 protein, human
  • PANX1 protein, human
  • Purinergic P2X Receptor Agonists
  • Receptors, Purinergic P2X7