Positive markers of epithelial-mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival. We discuss recent translational discoveries in EMT and suggest additional actionable molecular pathways, biomarkers, and clinical agents.
Keywords: Biomarkers; Clinical trials in HNSC; EMT and HPV; EMT head and Neck cancer; Slug; Snail; TGF beta and Head and Neck cancer.