Walking and psychomotor speed in the elderly: concordance, correlates and prediction of death

J Nutr Health Aging. 2015 Apr;19(4):468-73. doi: 10.1007/s12603-014-0560-y.

Abstract

Objectives: To investigate the concordance between walking (WS) and psychomotor speed (PS), correlates of both tasks, and their capacity to predict mortality in the elderly.

Design, setting and participants: Seven-year cohort study of 1,365 community-dwelling subjects aged 65-95 years, participating in the Bordeaux sample of the Three City Study, a French prospective cohort designed to evaluate the risk of cognitive decline attributable to vascular risk factors.

Measurements: Participants completed a battery of cognitive assessments including time to complete Trail Making Test A used as a PS measure, and a measure of WS. Socio-demographic determinants, co-morbidities, functional and cognitive evaluation, and incident mortality were taken into account.

Results: Mean age was 75.7 (SD ± 5.4) years. WS and TMT-A speed have very low concordance (kappa coefficient=.05). The correlates of each measure were different: mostly clinical co-morbidities for WS, and mostly cognition and function for TMT-A speed. However, TMT-A speed and WS are both independent predictors of death after seven years of follow-up.

Conclusion: WS and TMT-A speed could be considered as two different dimensions of age-related slowness, but both performances were associated with higher risk of mortality.

MeSH terms

  • Acceleration
  • Aged
  • Aged, 80 and over
  • Cognition / physiology
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / mortality
  • Comorbidity
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Mortality*
  • Prospective Studies
  • Psychomotor Performance / physiology*
  • Residence Characteristics
  • Risk Factors
  • Time Factors
  • Trail Making Test
  • Walking / physiology*