The aim of the work was to study the effects of mechanical stimulation of the soles' support zones on state of m. soleus motoneurone pool in man under 7-days support unloading conditions, which was provided by "Dry Immersion" model. Before, during and after immersion exposure the excitability of m. soleus motoneurone pool was estimated by H-reflex amplitude normalized by the maximal amplitude of M-wave. The data registered in two groups of volunteers: "control" in which only immersion exposure was used and "experimental" in which stimulation of support zones of sole was carried out during Dry Immersion were compared. During immersion relative amplitude of H-reflex increased in the control group. These alterations were not revealed in the experimental group with daily application of the support stimulation in natural locomotion regimens during immersion.