Will Sodium Intake Reduction Improve Cardiovascular Outcomes in the General Population? A Critical Review of Current Evidence

Curr Hypertens Rev. 2015;11(1):22-9. doi: 10.2174/1573402111666150530205428.

Abstract

The data associating blood pressure to salt intake in humans comes from randomized clinical trials of interventions on dietary salt intake and population studies. Generally, estimates from meta-analyses are similar to those derived from prospective population studies (1.7 mm Hg change in systolic blood pressure per 100 mmol change in 24-hour urinary sodium). This observation, however, does not translate into a higher risk of incidence rate of hypertension in individuals consuming a highsalt diet. On the other hand, prospective studies relating cardiovascular outcomes to 24-h urinary sodium excretion produced inconsistent conclusions. Thus, available evidence does not support current recommendations of an indiscriminate and generalized reduction of salt intake in the general population.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / mortality*
  • Cardiovascular Diseases / therapy
  • Humans
  • Hypertension / epidemiology
  • Risk Factors
  • Sodium / urine
  • Sodium, Dietary / administration & dosage*
  • Survival Analysis
  • Treatment Outcome

Substances

  • Sodium, Dietary
  • Sodium