Prevalence of and risk factors for late diagnosis of HIV infection in Brazilian infants and children

Rev Soc Bras Med Trop. 2015 May-Jun;48(3):326-30. doi: 10.1590/0037-8682-0257-2014.

Abstract

Introduction: Late human immunodeficiency virus (HIV) diagnosis is an important cause of HIV-related morbidity and mortality in infants and children.

Methods: This retrospective cohort study of HIV-infected children diagnosed in Sergipe, in northeastern Brazil, between 2002 and 2011 aimed to determine the prevalence of and risk factors for late HIV diagnosis.

Results: Of 55 infants and children with confirmed infection, 42 (76.5%) were diagnosed at ≥ 12 months old. No antiretroviral prophylaxis during delivery (OR 5.48, 95% CI 1.11-32.34) was associated with late diagnosis.

Conclusions: More than 75% of cases were diagnosed late. Efforts are needed to improve early HIV diagnosis in infants.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brazil / epidemiology
  • Child
  • Delayed Diagnosis / statistics & numerical data*
  • Epidemiologic Methods
  • Female
  • HIV Infections / diagnosis*
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • Humans
  • Infant
  • Infectious Disease Transmission, Vertical / statistics & numerical data*
  • Male