Using proteomics to probe neurons

Elife. 2015 Jul 2:4:e09103. doi: 10.7554/eLife.09103.

Abstract

Advances in mass spectrometry-based proteomics have allowed researchers to quantify the abundances of the different forms of three closely related proteins in the neurons of mice.

Keywords: MRM; SRM; alternative splicing; cell biology; mouse; neuroligin; neuroscience; recognition; synapse.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Adhesion Molecules, Neuronal / chemistry*
  • Mass Spectrometry / methods*
  • Membrane Proteins / chemistry*
  • Neurons / chemistry*
  • Protein Isoforms / chemistry*

Substances

  • Cell Adhesion Molecules, Neuronal
  • Membrane Proteins
  • Protein Isoforms