Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo

Affiliations

• ¹ Department of Pediatric Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.
• ² Research Laboratory, Nordland Hospital, Bodø, Norway.
• ³ Department of Pediatric Nephrology, and Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands Department of Pediatric Nephrology, University Hospitals, Leuven, Belgium.
• ⁴ Research Laboratory, Nordland Hospital, Bodø, Norway Department of Immunology, Oslo University Hospital, K.G. Jebsen Inflammation Research Centre, University of Oslo, Oslo, Norway Faculty of Health Sciences, K.G. Jebsen Thrombosis Research and Expertise Center, University of Tromsø, Tromsø, Norway Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.