Eighty-two couples were treated with gamete intrafallopian transfer (GIFT) in 93 treatment cycles. Twenty-three clinical pregnancies resulted. Pregnancies were obtained in 40% of the cases where 5 or more ova were placed in the Fallopian tubes. In the cases where 4 or fewer ova were transferred, the pregnancy rate was 12%. Three miscarriages and one ectopic pregnancy occurred. Sixteen of the pregnancies were singleton, there were 5 twins, 1 triplet and 1 quadruplet. According to the present material, GIFT seems to represent a significant improvement in selected groups of patients.