Coproduction of KPC-2 and QnrB19 in Klebsiella pneumoniae ST340 isolate in Brazil

Diagn Microbiol Infect Dis. 2015 Dec;83(4):375-6. doi: 10.1016/j.diagmicrobio.2015.09.003. Epub 2015 Sep 9.

Abstract

Few reports described the presence of bla(KPC) and qnr genes in the same isolate. This study reports the combination of bla(KPC-2) and qnrB19 genes in Klebsiella pneumoniae ST340 isolate in Brazil. These findings draw attention to this combination in ST340 isolate, which is part of the CC258, disseminated in Latin America.

Keywords: CC258; Carbapenemase; Quinolone resistance; ST340.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Brazil
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Klebsiella Infections / microbiology*
  • Klebsiella pneumoniae / enzymology*
  • Klebsiella pneumoniae / genetics
  • Klebsiella pneumoniae / isolation & purification
  • Male
  • Middle Aged
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • Bacterial Proteins
  • Qnr protein, Klebsiella pneumoniae
  • beta-lactamase KPC-2
  • beta-Lactamases