Cardiac arrest and therapeutic hypothermia

Michael G Silverman; Benjamin M Scirica

doi:10.1016/j.tcm.2015.10.002

Cardiac arrest and therapeutic hypothermia

Trends Cardiovasc Med. 2016 May;26(4):337-44. doi: 10.1016/j.tcm.2015.10.002. Epub 2015 Oct 22.

Authors

Michael G Silverman¹, Benjamin M Scirica²

Affiliations

¹ Cardiovascular Division, Department of Medicine, Brigham and Women׳s Hospital, Boston, MA. Electronic address: mgsilverman@partners.org.
² Cardiovascular Division, Department of Medicine, Brigham and Women׳s Hospital, Boston, MA.

PMID: 26603661
DOI: 10.1016/j.tcm.2015.10.002

Abstract

Therapeutic hypothermia for patients who remain comatose following resuscitation from a cardiac arrest improves both survival and neurologic outcomes. Although this therapy has been incorporated into the guidelines for routine post-resuscitation care and has been in clinical use for over a decade, significant questions and controversies remain. In this review, we discuss these questions in the context of the current evidence and provide a practical framework to help guide clinicians.

Keywords: Cardiac arrest; targeted temperature management; therapeutic hypothermia.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Body Temperature Regulation*
Heart Arrest / diagnosis
Heart Arrest / mortality
Heart Arrest / physiopathology
Heart Arrest / therapy*
Humans
Hypothermia, Induced* / adverse effects
Hypothermia, Induced* / mortality
Recovery of Function
Resuscitation* / adverse effects
Resuscitation* / mortality
Time Factors
Treatment Outcome