Iatrogenic Necrolytic Migratory Erythema in an Infant with Congenital Hyperinsulinism

Pediatr Dermatol. 2016 Mar-Apr;33(2):e43-7. doi: 10.1111/pde.12741. Epub 2015 Dec 9.

Abstract

Necrolytic migratory erythema (NME) is a rare cutaneous finding characterized by painful, pruritic, scaly red patches and plaques, bullae, and superficial erosions. Typically NME is a paraneoplastic phenomenon associated with glucagonoma. We report the exceptional case of an infant who developed iatrogenic NME arising secondary to glucagon therapy for congenital hyperinsulinism.

Publication types

  • Case Reports

MeSH terms

  • Congenital Hyperinsulinism / drug therapy*
  • Female
  • Glucagon / adverse effects*
  • Glucagon / therapeutic use
  • Humans
  • Iatrogenic Disease
  • Infant
  • Necrolytic Migratory Erythema / chemically induced*
  • Necrolytic Migratory Erythema / diagnosis
  • Skin / pathology*

Substances

  • Glucagon