Effect of Omega-3 and Vitamins E + C Supplements on the Concentration of Serum B-Vitamins and Plasma Redox Aminothiol Antioxidant Status in Elderly Men after Strength Training for Three Months

Ann Nutr Metab. 2016;68(2):145-55. doi: 10.1159/000443847. Epub 2016 Feb 6.

Abstract

Background: Data on redox plasma aminothiol status in individuals on strength training are very limited. Therefore, we studied the effect of omega-3 and vitamins E + C supplementation on the concentration of B-vitamins and redox aminothiol status in elderly men after strength training for 3 months.

Methods: Healthy men, age 60 ± 6 (mean ± SD) were randomly divided into 3 groups: group I received placebo (n = 17), group II consumed omega-3 (700 mg, n = 17), and group III consumed vitamins E + C (235 mg +1 g, n = 16) daily for 3 months. All participants completed a strength training program for the same period.

Results: The concentration of serum vitamin B12 decreased and the concentration of serum folate increased in group I after the intervention (p = 0.01, p = 0.009). The concentration of plasma 5-pyridoxal phosphate decreased in groups II and III (p = 0.03 and p = 0.01), whereas the concentration of serum uric acid decreased only in group II (p = 0.02). We detected an increase in the concentration of reduced form of aminothiols in all groups (p < 0.001). The red/ox plasma aminothiol status was significantly changed in all groups after the intervention (p < 0.05).

Conclusion: Omega-3 and vitamins E + C supplementation affect the concentrations of serum B-vitamins and redox plasma aminothiol status in healthy elderly men on strength training.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antioxidants / analysis*
  • Ascorbic Acid / pharmacology*
  • Dietary Supplements
  • Fatty Acids, Omega-3 / pharmacology*
  • Folic Acid / blood
  • Humans
  • Male
  • Middle Aged
  • Pyridoxal / blood
  • Resistance Training*
  • Sulfhydryl Compounds / blood*
  • Uric Acid / blood
  • Vitamin B 12 / blood
  • Vitamin B Complex / blood*
  • Vitamin E / pharmacology*
  • Vitamins / pharmacology*

Substances

  • Antioxidants
  • Fatty Acids, Omega-3
  • Sulfhydryl Compounds
  • Vitamins
  • Vitamin B Complex
  • Vitamin E
  • Uric Acid
  • Pyridoxal
  • Folic Acid
  • Vitamin B 12
  • Ascorbic Acid