Sex and HIV serostatus differences in decision making under risk among substance-dependent individuals

J Clin Exp Neuropsychol. 2016;38(4):404-15. doi: 10.1080/13803395.2015.1119806.

Abstract

HIV+ individuals with and without substance use disorders make significantly poorer decisions when information about the probability and magnitude of wins and losses is not available. We administered the Game of Dice Task, a measure of decision making under risk that provides this information explicitly, to 92 HIV+ and 134 HIV- substance-dependent men and women. HIV+ participants made significantly poorer decisions than HIV- participants, but this deficit appeared more prominent among HIV+ women. These data indicate that decision making under risk is impaired among HIV+ substance-dependent individuals (SDIs). Potential factors for the HIV+ women's relatively greater impairment are discussed.

Keywords: HIV; decision making; drug abuse; executive function; sex differences.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Decision Making / physiology*
  • Executive Function / physiology
  • Female
  • HIV Infections / psychology*
  • Humans
  • Male
  • Middle Aged
  • Personality Inventory
  • Risk-Taking*
  • Severity of Illness Index
  • Sex Characteristics*
  • Statistics, Nonparametric
  • Substance-Related Disorders / physiopathology*