Chromosome abnormalities in a pancreatic adenocarcinoma

B Johansson; N Mandahl; S Heim; F Mertens; A Andrén-Sandberg; F Mitelam

doi:10.1016/0165-4608(89)90050-2

Chromosome abnormalities in a pancreatic adenocarcinoma

Cancer Genet Cytogenet. 1989 Feb;37(2):209-13. doi: 10.1016/0165-4608(89)90050-2.

Authors

B Johansson¹, N Mandahl, S Heim, F Mertens, A Andrén-Sandberg, F Mitelam

Affiliation

¹ Department of Clinical Genetics, University Hospital, Lund, Sweden.

PMID: 2702620
DOI: 10.1016/0165-4608(89)90050-2

Abstract

Short-term cultures initiated from a pancreatic adenocarcinoma were cytogenetically investigated. The composite karyotype was 74-76,XX,+X,+2,+3,+del(3)(p21),+5,+5,+der(7) t(1;7)(q21;p22),+der(7),del(8)(p21),+del(8)(p21),+der(8)t(8;?)(q24; +),+9,+9,+10,+10,+11,+11,+12,+13,+14,+der(14)t(14; +)(p11;?),+der(16)t(15;16)(q11;p13),+der(16),+der(17)t(17;?) (p11;?),+der(17),+18,+20,+20,-21,-21,+22,+22,+1-3mar. A comparison with the few previously cytogenetically characterized cases of this tumor type reveals no consistent abnormalities.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adenocarcinoma / genetics*
Aged
Chromosome Aberrations*
ErbB Receptors / genetics
Female
Humans
Karyotyping
Pancreatic Neoplasms / genetics*

Substances

ErbB Receptors