Weekend Effect in Children With Stroke in the Nationwide Inpatient Sample

Stroke. 2016 Jun;47(6):1436-43. doi: 10.1161/STROKEAHA.116.013453. Epub 2016 Apr 26.

Abstract

Background and purpose: Studies have demonstrated differences in clinical outcomes in adult patients with stroke admitted on weekdays versus weekends. The study's objective was to determine whether a weekend impacts clinical outcomes in children with ischemic stroke and hemorrhagic stroke.

Methods: Children aged 1 to 18 years admitted to US hospitals from 2002 to 2011 with a primary discharge diagnosis of ischemic stroke or hemorrhagic stroke were identified by International Classification of Disease, 9th Revision, codes. Logistic regression estimated odds ratios and 95% confidence intervals for in-hospital mortality and discharge to a nursing facility among children admitted on weekends (Saturday and Sunday) versus weekdays (Monday to Friday), adjusting for potential confounders.

Results: Of 8467 children with ischemic stroke, 28% were admitted on a weekend. Although children admitted on weekends did not have a higher in-hospital mortality rate than those admitted on weekdays (4.1% versus 3.3%; P=0.4), children admitted on weekends had a higher rate of discharge to a nursing facility (25.5% versus 18.6%; P=0.003). After adjusting for age, sex, and confounders, the odds of discharge to a nursing facility remained increased among children admitted on weekends (odds ratio, 1.5; 95% confidence interval, 1.1-1.9; P=0.006). Of 10 919 children with hemorrhagic stroke, 25.3% were admitted on a weekend. Children admitted on weekends had a higher rate of in-hospital mortality (12% versus 8%; P=0.006). After adjusting for age, sex, and confounders, the odds of in-hospital mortality remained higher among children admitted on weekends (odds ratio, 1.4; 95% confidence interval, 1.1-1.9; P=0.04).

Conclusions: There seems to be a weekend effect for children with ischemic and hemorrhagic strokes. Quality improvement initiatives should examine this phenomenon prospectively.

Keywords: International Classification of Diseases; hospital mortality; hospitalization; intracranial hemorrhages; stroke.

MeSH terms

  • Adolescent
  • Age Factors
  • Brain Ischemia / epidemiology
  • Child
  • Child, Preschool
  • Female
  • Hospital Mortality
  • Hospitalization / statistics & numerical data
  • Humans
  • Infant
  • Inpatients
  • International Classification of Diseases
  • Intracranial Hemorrhages / epidemiology
  • Male
  • Patient Discharge / statistics & numerical data
  • Seizures / epidemiology
  • Seizures / etiology
  • Sex Factors
  • Stroke / epidemiology
  • Stroke / therapy*
  • Treatment Outcome
  • United States / epidemiology