Live Cell Imaging of ABCA1 Downregulation by HIV-1 Nef in an Experimental Model of HeLa ABCA1-GFP

AIDS Res Hum Retroviruses. 2016 Sep;32(9):872-3. doi: 10.1089/aid.2015.0362. Epub 2016 May 2.

Authors

Johanna Siegel¹, Christina Darwish¹, Anastas Popratiloff², Michael Bukrinsky¹, Beda Brichacek¹

Affiliations

¹ 1 School of Medicine and Health Sciences, George Washington University , Washington, District of Columbia.
² 2 Office of VP for Research, Center for Microscopy and Image Analysis, George Washington University , Washington, District of Columbia.

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

ATP Binding Cassette Transporter 1 / analysis
ATP Binding Cassette Transporter 1 / biosynthesis*
Down-Regulation*
Green Fluorescent Proteins / analysis
HeLa Cells
Host-Pathogen Interactions*
Humans
Intravital Microscopy
Microscopy, Fluorescence
Models, Theoretical
Recombinant Fusion Proteins / analysis
nef Gene Products, Human Immunodeficiency Virus / metabolism*

Substances

ABCA1 protein, human
ATP Binding Cassette Transporter 1
Recombinant Fusion Proteins
nef Gene Products, Human Immunodeficiency Virus
nef protein, Human immunodeficiency virus 1
Green Fluorescent Proteins

Grants and funding