Etiopathogenesis, prediction, and prevention of preeclampsia

Hypertens Pregnancy. 2016 Aug;35(3):280-94. doi: 10.1080/10641955.2016.1181180. Epub 2016 Jun 17.

Abstract

Hypertensive disorders are a major cause of maternal death. Preeclampsia (PE) affects about 5% of pregnancies and is associated to high cardiovascular death risk. Understanding of its origin and cause is difficult and many etiologies have been proposed. So far, little can be done for real prevention and the only treatment is pregnancy interruption, increasing the child's risk for prematurity complications. Early markers of disease are a promising path for understanding the pathogenesis and developing new strategies for prediction and eventually disease prevention.

Keywords: Aspirin; Doppler; prediction; preeclampsia; prevention.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Pre-Eclampsia / etiology*
  • Pre-Eclampsia / physiopathology
  • Pre-Eclampsia / prevention & control*
  • Pregnancy
  • Pregnancy Trimester, First
  • Risk Factors