Intravascular migration of contraceptive implants: two more cases

Contraception. 2017 Feb;95(2):211-214. doi: 10.1016/j.contraception.2016.07.015. Epub 2016 Jul 21.

Abstract

Cases: In addition to previously published case reports, further cases of intravascular migration of contraceptive implants have been identified from an information request to two national adverse reaction spontaneous reporting systems. We report on two new cases of insertion into the venous system with subsequent embolism to a pulmonary artery.

Conclusion: Incorporating barium sulfate into the implant has facilitated diagnosis of these very rare adverse events with the initial diagnosis of embolism to the pulmonary arterial tree made by chest X-ray. Removal of an implant from a segmental branch of a pulmonary artery is technically challenging and not without risks. Unsuccessful removal appears to be preceded by a delay in diagnosis leading to endothelialization of the implant in the pulmonary arterial wall.

Implications: Subdermal placement of contraceptive implants over the anterior surface of the biceps rather than in the sulcus between the biceps and triceps may negate this rare but reported risk.

Keywords: Contraceptive implant; Intravascular; Lung; Pulmonary artery; Pulmonary embolism.

Publication types

  • Case Reports

MeSH terms

  • Arm
  • Barium Sulfate / administration & dosage
  • Contraceptive Agents, Female / administration & dosage*
  • Contrast Media
  • Desogestrel / administration & dosage
  • Drug Implants / adverse effects*
  • Equipment Failure
  • Female
  • Foreign-Body Migration* / complications
  • Foreign-Body Migration* / diagnostic imaging
  • Humans
  • Pulmonary Artery*
  • Pulmonary Embolism / diagnostic imaging
  • Pulmonary Embolism / etiology*
  • United Kingdom

Substances

  • Contraceptive Agents, Female
  • Contrast Media
  • Drug Implants
  • Barium Sulfate
  • etonogestrel
  • Desogestrel