[Stimulation of spermatogenesis: For whom? Why? How?]

Abstract

The stimulation of spermatogenesis is the best treatment of infertility for male hypogonadotropic-hypogonadism. The results are very pleasing because a real improvement of semen is sometimes obtained with spontaneous pregnants describing in the literature but after a long duration of treatment, often many months. Sometimes, the treatment improves the technical conditions of ICSI for the embryologists. Stimulation of spermatogenesis by gonadotrophins rFSH and/or hCG is the most used but others treatments, like pulsatile GnRH therapy or clomifene citrate can be used. The purpose of this review is to described the different protocols of stimulation of spermatogenesis and explain their results and finally to see if others indications of stimulation of spermatogenesis are existing.

Keywords: Citrate de clomifène; Clomifene citrate; Gonadotrophines; Gonadotropins; Hypogonadisme hypogonadotrope; Hypogonadotropic-hypogonadism; Infertilité masculine; Male infertility; Pompe à GnRH; Pulsatile GnRH therapy; Stimulation de la spermatogenèse; Stimulation of spermatogenesis.