Diffusion-weighted Imaging Using Readout-segmented EPI Reveals Bony Metastases from Neuroblastoma

J Pediatr Hematol Oncol. 2016 Oct;38(7):e263-6. doi: 10.1097/MPH.0000000000000643.

Abstract

Identifying neuroblastoma (NBL) metastases is crucial to treatment and prognosis. Metaiodobenzylguanidine and Tc99M bone scans are standard for identifying bony metastases but can underestimate disease. Diffusion-weighted imaging (DWI) of the spine has shown promise in evaluating bony metastases but has been limited by artifacts. Readout-segmented echo planar imaging is a technique for DWI that minimizes artifacts allowing for improved identification of spinal disease. This report illustrates the utility of DWI of the spine using readout-segmented echo planar imaging in the detection of bony NBL metastases in a child, lending support that DWI should be included in magnetic resonance imaging scans for NBL.

Publication types

  • Case Reports

MeSH terms

  • 3-Iodobenzylguanidine
  • Bone Neoplasms / secondary*
  • Child, Preschool
  • Echo-Planar Imaging / methods*
  • Humans
  • Male
  • Neuroblastoma / diagnostic imaging*
  • Neuroblastoma / pathology
  • Spine / diagnostic imaging*

Substances

  • 3-Iodobenzylguanidine