[Cardiac support and replacement therapies]

Anasthesiol Intensivmed Notfallmed Schmerzther. 2016 Sep;51(9):564-72. doi: 10.1055/s-0041-109831. Epub 2016 Sep 15.
[Article in German]

Abstract

Circulatory support represents an integral part within the treatment of the critically ill patient. Sophisticated pharmacologic regimens help to maintain systemic perfusion pressure by increasing vascular tone as well as mediating positive inotropic effects. Besides the administration of catecholamines and phosphodiesterase-III-inhibitors, in particular the administration of levosimendan represents a promising alternative during low-cardiac-output. Nevertheless, sufficient evidence demonstrating a survival benefit for any pharmacologic regimen is nonexistent. In case pharmacological measures do not suffice mechanical cardiopulmonary support (MCS) may be used. MCS may be used during cardiopulmonary resuscitation or a "low-cardiac-output-syndrome" as bridging towards decision, recovery or long-term support. Venoarterial extracorporeal membrane oxygenation (vaECMO) may take over cardiopulmonary function and may improve survival as well as neurological outcome after cardiogenic shock or cardiopulmonary resuscitation.

Publication types

  • Review

MeSH terms

  • Cardiotonic Agents / administration & dosage*
  • Combined Modality Therapy / methods
  • Critical Care / methods
  • Evidence-Based Medicine
  • Extracorporeal Membrane Oxygenation / methods*
  • Heart Failure / diagnosis
  • Heart Failure / therapy*
  • Heart Transplantation / instrumentation
  • Heart Transplantation / methods*
  • Heart-Assist Devices*
  • Humans
  • Treatment Outcome

Substances

  • Cardiotonic Agents